Publications
2010 - Present

Rabbany SY, Rafii S. Blood flow forces liver growth. Nature. 2018 Oct;562(7725):42-43. PMID: 30275551

Merna N, Wong AK, Barahona V, Llanos P, Kunar B, Palikuqi B, Ginsberg M, Rafii S, Rabbany SY. Laminar shear stress modulates endothelial luminal surface stiffness in a tissue-specific manner. Microcirculation. 2018 Jul;25(5):e12455. Epub 2018 May 30. PMID: 29665185

Guo P., Poulos M.G., Palikuqi B, Badwe C.R., Lis R., Kunar B. Ding B., Rabbany S.Y., Shido K., Butler J.M., Rafii S. (2017). Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression. J Clin Invest. 2017 Dec 1;127(12):4242-4256. Epub 2017 Oct 23. PMID:29058691

Poulos M.G., Ramalingam P., Gutkin M.C., Llanos P., Gilleran K., Rabbany S.Y., Butler J.M. (2017). Endothelial transplantation rejuvinates aged hematopoietic stem cell function. J Clin Invest. 2017 Nov 1; 127(11):4163-4178. Epub 2017 Oct 16. PMID:29035282

Benedicto I., Lehmann G.L., Ginsberg M, Nolan D.J., Bareja R, Elemento O, Salfati Z, Alam N.M., Prusky GT, Llanos P, Rabbany S.Y., Maminishkis A, Miller SS, Rafii S, Rodriguez-Boulan E. (2017). Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors. Nature Communication. 2017 May 19;8:15374. PMID:28524846.

de Guzman R.C., Rabbany S.Y. (2016). PEG-Immobilized Keratin for Protein Drug Sequestration and pH-Mediated Delivery. Hindawi Journal of Drug Delivery. 2016;2016:7843951. Epub 2016 Jan 20. PMID:26904294

Cao Z., Lis R., Ginsberg M., Chavez D., Shido K., Rabbany S.Y., Fong G.H., Sakmar T.P., Rafii S., Ding B.S. (2016). Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis. Nature Medicine. 2016 Feb;22(2):154-62. Epub 2016 Jan 18. PMID:26779814
Wong A.K., Llanos P., Boroda N., Rosenberg S.R., and Rabbany S.Y. (2015). A Parallel-Plate Flow Chamber for Mechanical Characterization of Endothelial Cells Exposed to Laminar Shear Stress. Cellular and Molecular Bioengineering.2016 Mar;9(1):127-138. Epub 2015 Oct 27. PMID:28989541
Rafii, S., Cao, Z, Lis, R, Siempos, I.I., Chavez, D., Shido, K., Rabbany, S.Y., Ding, B.S. (2015). Platelet-derived ​SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration. Nat Cell Biol. 2015 Feb;17(2):123-136. Epub 2015 Jan 26. PMID:25621952
Ding, B.S., Cao, Z, Lis, R, Nolan, D.J., Guo, P., Simons, M., Penfold, M.E., Shido, K., Rabbany, S.Y., Rafii, S. (2014). Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis. Nature. 2014 Jan 2;505(7481):97-102. Epub 2013 Nov 20. PMID:24256728
Yamamoto, M., Rafii, S., Rabbany, S.Y. (2014). Scaffold biomaterials for nano-pathophysiology. Adv Drug Deliv Rev. 74C:104-114. PMID:24075835
Ding, B.S., James, D., Iyer, R., Falciatori, I., Hambardzumyan, D., Wang, S., Butler, J.M., Rabbany, S.Y., Hormigo, A. (2013). Prominin 1/CD133 endothelium sustains growth of proneural glioma. PLoS One. 505(7481) PMID:23637986
Nolan, D.J., Ginsberg, M., Israely, E., Palikuqi, B., Poulos, M.G., James, D., Ding, B.S., Schachterle, W., Liu, Y., Rosenwaks, Z., Butler, J.M., Xiang, J., Rafii, A., Shido, K., Rabbany, S.Y., Elemento, O., Rafii, S. (2013) Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration. Development Cell. 26(2):204-19. PMID:23871589
Israely, E., Ginsberg, M., Nolan, D., Ding, B.S., James, D., Elemento, O., Rafii, S., Rabbany, S.Y. (2013) Akt suppression of TGFβ signaling contributes to the maintenance of vascular identity in embryonic stem cell-derived endothelial cells. Stem Cells. (Aug 20 - Epub ahead of print) PMID:23963623
Ginsberg, M., James, D., Ding, B.S., Nolan, D., Geng, F., Butler, J.M., Schachterle, W., Pulijaal, V.R., Mathew, S., Chasen, S.T., Xiang, J., Rosenwaks, Z., Shido, K., Elemento, O., Rabbany, S.Y., Rafii, S.  (2012) Efficient direct reprogramming of mature human amniotic cells into endothelial cells by ETS factors and TGFβ suppression. Cell, In Press, 2012. PMID:23084400
Benezra, M., Phillips, E., Tilki, D., Ding, B.S., Butler, J., Dobrenkov, K., Siim, B., Chaplin, D., Rafii, S., Rabbany, S., Bradbury, M.S. (2012) Serial monitoring of human systemic and xenograft models of leukemia using a novel vascular disrupting agent. Leukemia. 2012 Aug;26(8):1771-8. Epub 2012 Feb 20. PMID:22343591
Ding, B.S., Nolan, D.J., Peipei, G., Babazadeh, A.O., Cao, Z., Rosenwaks, Z., Crystal, R.G., Simons, M., Sato, T.N., Worgall, S., Shido, K., Rabbany, S.Y., Rafii, S. (2011) Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell, 47(3):539-53. PMID:22036563.
Henderson, P.W., Singh, S.P., Krijgh, D.D., Yamamoto, M., Rafii, D.C., Sung, J.J.,, Rafii, S., Rabbany S.Y., Spector JA.  (2011) Stromal-derived factor-1 delivered via hydrogel drug-delivery vehicle accelerates wound healing in vivo. Wound Repair Regen. 2011 Apr 21. [Epub ahead of print] PMID:21518091
Agarwal, U., Ghalayini, W., Dong, F., Weber, K., Zou, Y.R., Rabbany, S.Y., Rafii, S., Penn, M.S. (2010) Role of Cardiac Myocyte CXCR4 Expression in Development and Left Ventricular Remodeling After Acute Myocardial Infarction. Circ Res. 107(5):667-76. PMID:20634485
Ding, B., Nolan, D., Butler, J., James, D., Babazadeh, A.O., Rosenwaks, Z., Mittal, V., Kobayashi H., Shido, K., Lyden, D., Sato, T., Rabbany, S.Y., Rafii, S. (2010) Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration. Nature 468(7321):310-5. (Rabbany, S.Y. is co-senior author) PMID:21068842
James, D., Nam, H., Seandel, M., Nolan, B., Janovitz, T., Tomishima, M., Studer, L., Lee, G., Lyden, D., Benezra, R., Zaninovic, N., Rosenwaks, Z.,  Rabbany, S.Y., Rafii S. (2010) Expansion and Maintenance of Human Vasculogenic Embryonic Stem Cell-derived Endothelial Cells by TGFβ Inhibition is Id1 Dependent. Nature Biotechnology, 28(2):161-6. PMID:20081865 (Rabbany, S.Y. is co-senior author)
Rabbany, S.Y., James, D., Rafii, S. (2010) New Dimensions in Vascular Engineering: Opportunities for Cancer Biology.  Tissue Eng Part A. 16(7):2157-9. PMID:20367255
Rabbany, S.Y., Pastore, J., Yamamoto, M., Miller, T., Rafii, S., Aras, R., Penn, M.  (2010) Continuous Delivery of Stromal Cell-Derived Factor-1 from Alginate Scaffolds Accelerates Wound Healing. Cell Transplantation, 19(4):399-408. PMID:19995484
Yamamoto, M., James, D., Li, H., Butler, J., Rafii, S., Rabbany, S.Y. (2010) Generation of Stable Co-cultures of Vascular Cells in a Honeycomb Alginate Scaffold. Tissue Engineering, Part A –16:299-308. PMID:19705957

2000 - 2010


James, D., Rabbany, S.Y., Rafii S. (2008) Hitting the mother lode of tumor angiogenesis.  Nature Biotechnology 26(7):769-70. PMID:18612297
Seandel, M., Butler, J., Kobayashi, H., Hooper, A., White, I., Zhang, F., Vertes, E.L., Kobayashi, M., Zhang, Y., Shmelkov, S., Hackett, N., Rabbany, S.Y., Boyer, J., Rafii S. (2008)   Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene. Proceedings of National Academy of Sciences (PNAS) 105:19287–92. PMID:19036927
Rabbany, S.Y., and Rafii, S. (2007) Book Review - Cell of Cells: The Global Race to Capture and Control the Stem Cell.  Journal of Clinical Investigation. 117:2349. PMID:1952641
Shmelkov, S.V., Meeus, S., Moussazadeh, N., Kermani, P., Rashbaum, W.K., Rabbany, S.Y., Hanson, M.A., Lane, W.J., St. Clair, R., Walsh, K.A., Dias, S., Jacobson, J.T., Hempstead, B.L., Edelberg, J.M., Rafii, S. Cytokine preconditioning promotes codifferentiation of human fetal liver CD133+ stem cells into angiomyogenic tissue. Circulation. 111:1175-83, 2005. PMID:16240088 [Abstract]
Vincent, L., Avancena, P., Cheng, J., Rafii, S., Rabbany, S.Y. Simulated microgravity impairs leukemic cell survival through altering VEGFR-2/VEGF-A signaling pathway. Annals of Biomedical Engineering, 33:1405-10, 2005. PMID:12657432 [Abstract]
Rabbany, S.Y., Heissig, B., Hattori, K., and Rafii, S. (2003) Molecular pathways regulating mobilization of marrow-derived stem cells for tissue revascularization. Trends in Molecular Medicine 9;3:109-117. PMID: 12657432 [Abstract]
Role of Mechanical Forces on the Trafficking of Hematopoietic Cells. Proceeding of Keystone Symposia, No. 3064, 2003, 131.
Rabbany, S.Y., Danielson, M., and Noordergraaf, A. (2001) A Brief Assessment of Myocardial Viability in Surgically Remoldeled Heart. Cardiovascular Engineering: An International J. 1(3):155-161.
Lane, W.J., Dias, S., Hattori K., Heissig, B., Choy, M., Rabbany, S.Y., Wood, J., Moore, M.A., and Rafii, S. (2000) SDF-1 induced megakaryocytes migration and platelet production is dependent on matrix metalloproteinases. Blood 15;96:4152-9. PMID:11110686 [Abstract]
Rabbany, S.Y., Lane, W.J., Tabaksblat, M., and Rafii, S. (2000) Shear Stress Induced Modulation of Human Vascular Endothelial Growth Factor Receptors (VEGFR-1 & VEGFR-2). Heart and Vessels, Suppl. 13:41,E12.
Rabbany, S. Y., Lane, W.J., Marganski, W.A., Kusterbeck, A. W., and Ligler, F.S. (2000) Trace Detection of Explosives Using a Membrane-base Displacement Immunoassay. Journal of Immunological Methods 246:69-77. PMID: 11121548 [Abstract]

1990 - 2000


FGF-2 Induces Angiogenesis by Upregulating VEGFR-2 (KDR). Biophysical Journal, 76(1), A151, 1999.
Holt, D. B., Rabbany, S. Y., Kusterbeck, A. W., and Ligler, F. S. (1999) Advances in Flow Displacement Immunoassay Design.  Reviews in Analytical Chemistry 18:107-132.
Rabbany, S. Y., Marganski, W.A., Kusterbeck, A.W., and Ligler, F. S. (1998) A Membrane-based Displacement Flow Immunoassay. Biosensors and Bioelectronics 13:939-944. PMID: 9839382
Rabbany, S. Y., Piervincenzi, R. T., Kusterbeck, A. W., Bredehorst, R., and Ligler, F. S. (1998) Dissociation  Rate Kinetics in a Solid-Phase Flow Immunoassay.  Analytical Letters, 31(10):1663-1675.
Rabbany, S. Y. (1998) New-Age Rapid Diagnosis of Acute Myocardial Injury. In: Analysis and Assessment of Cardiovascular Function. Edited by: G. Drzewiecki and J. Li, 128-141.
Rabbany, S. Y., Kresh, J. Y., and Noordergraaf, A.  (1997) Differentiation of Intramyocardial Fluid Pressure from Fiber Stress.  Journal of the Health Care and Technology, 5:145-157. PMID: 9134626 [Abstract]
Palladino, J. L., Rabbany, S. Y., Muiler, J. P. , and Noordergraaf, A.  (1997) A Perspective on Myocardial Contractility. Journal of the Health Care and Technology, 5:135-144. PMID:9134625 [Abstract]
Rabbany, S. Y., Piervincenzi, R. T., Judd, L., Kusterbeck, A. W., Bredehorst, R., and Ligler, F. S. (1997) Assessment of Heterogeneity in Antibody-Antigen Displacement Reactions. Analytical Chemistry, 69:175-182. PMID: 8997894 [Abstract]
Selinger, J. V., and Rabbany, S. Y. (1997) Theory of Heterogeneity in Displacement Reactions.  Analytical Chemistry, 69:170-174.
Rabbany, S. Y., Donner, B.L., and Ligler, F. S. (1994) Optical Immunosensors. Critical Reviews in Biomedical Engineering 22(5/6):307-346. PMID:8031193 [Abstract]
Rabbany, S. Y., Kusterbeck, A. W., Bredehorst, R., and Ligler, F. S. (1994) Binding Kinetics of Immobilized Antibodies in a Flow Immunosensor.  Sensors and Actuators, 29(1-3):72-78.
Golden, J. P., Anderson, G. P., Rabbany, S. Y., and Ligler, F. S. (1994) Fiber Optic-Based Biosensors: Fluorescent Signal Acquisition from Continuously Tapered Probes.  IEEE Transactions on Biomedical Engineering, 41(6):585-591. [Abstract]
Rabbany, S. Y., Funai, J., and Noordergraaf, A. (1994) Pressure Generation in a Contracting Myocyte.  Heart and Vessels Journal, 9(4):169-174. PMID: 7961293 [Abstract]
Rabbany, S. Y., Kusterbeck, A. W., Bredehorst, R., Ligler, F. S. (1994) Effect of Antibody Density on the Displacement Kinetics of a Flow Immunoassay.  Journal of Immunological Methods, 168:227-234. PMID:8308297 [Abstract]
Rabbany, S. Y., Drzewiecki, G., and Noordergraaf, A. (1993) Peripheral Vascular Effects on Auscultatory Blood Pressure Measurement. Journal of Clinical Monitoring, 9:9-17. PMID:8463815 [Abstract]
Ligler, F. S., and Rabbany, S. Y.  (1992)  Biological Microstructures in Biosensors.  In: Synthetic Microstructures in Biological Research, Edited by J. M. Schnur and M. Peckerar, Plenum Press 67-75.
Wemhoff, G. A., Rabbany, S. Y., Kusterbeck, A. W., Ogert, R. A., Bredehorst, R., and Ligler, F. S. (1992) Kinetics of Antibody Binding at Solid-Liquid Interfaces in Flow. Journal of Immunological Methods, 156:223-230. PMID: 1474258 [Abstract]
Rabbany, S. Y.  (1991)  The Genesis of Intramyocardial Pressure. Ph.D. Dissertation, University of Pennsylvania, Philadelphia.  Available from University Microfilms, Ann Arbor, MI.

Patents

Engineering Vascularized Networks in a Three Dimensional Physiological Structures (2010, Pending)
Growth Factors (Angiocrine) Produced by Endothelium Supports Liver Regeneration (2010, Pending)