Sina Rabbany Ph.D

Academic Affiliations

Jean Nerken Distinguished Professor of Engineering
Professor and Director of Bioengineering
Hofstra University
Hempstead NY 11549

Associate (Adjunct) Professor of Bioengineering in Genetic Medicine
Department of Medicine
Weill Cornell Medical College
New York, NY 10065

Education (Bioengineering):

   Ph.D. University of Pennsylvania, 1991
   M.S.E. University of Pennsylvania, 1986
   B.S.E. University of Pennsylvania, 1985

 

Current Status:

Research:

Dr. Rabbany is currently doing research in the field of cellular and tissue engineering as applied to the vascular system. One of the major obstacles in engineering vascularized tissue is induction of endothelial vessel networks. To this end, his research applies engineering principles to the advancements being made in the differentiation of embryonic stem (ES) cells toward engineering vascularized tissue. The focus of the research is to expand pure populations of stem cells in vitro, and influence their cell fate decisions to direct differentiation into vascular cells including functional transplantable endothelial (EC) and smooth muscle (SM) cells. Understanding the mechanistic basis of ES cell differentiation into functional ECs is critical to various aspects of tissue engineering and regenerative medicine. In addition, tissue explants generated by these vascular cells can be introduced in vivo to restore function by augmenting vessel growth, in the ischemic myocardium or limbs of patients after heart attacks or diabetic vascular diseases. The projects range from elucidating the role of physical forces such as cyclic stretch, simulated microgravity, and shear stress on vascular cells and engineering of vascularized constructs. In the past, he has done research in the areas of cardiovascular Mechanics and Biosensors, and cell & receptor biomechanics.

Recent Publications:

NatureTissue EngineeringCell TransplantationNature BiotechnologyCirculation ResearchWound Repair And RegenerationPNATissue Engineering Part A

Patents:

Contact Information:
   Hofstra University Weill Cornell Medical College
Phone: (516) 463-6672 (Office)
(516) 463-4718 (Lab)
(212) 746-7014 (Office)
(212) 746-2017 (Lab)
Fax: (526) 463-4939 (212) 746-8481
Office: 110 Weed Hall Rm A-863
  Email: Sina.Y.Rabbany@hofstra.edu sir2007@med.cornell.edu
Map: Directions to Lab Directions to Lab
URL: http://people.hofstra.edu/faculty/Sina_Y_Rabbany

 

Dr.Rabbany